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2019, October 4-7: Common and Challenging Diagnostic Dilemmas on Frozen Section Service


October 04-07, 2019 - Palm Springs, California

24 CME / 24 SAMs

Course Schedule     Faculty Biographies


Frozen section diagnosis can be challenging, particularly when the pathologist is handling the case alone. This difficulty may be compounded by dramatic and irreversible surgical implications. Frozen section interpretation is totally based on the histologic features since ancillary testing, including immunohistochemistry and molecular studies are not available. Time is crucial to make a confident diagnosis because the patient is on the operating table under general anesthesia, and the surgeon needs to know a specific answer to make a decision on the subsequent procedure. This is one of the times that a pathologist guides the hands of a surgeon.

The intra-operative consultation service is a critical component of a hospital-based pathology practice; it involves every sub-specialty surgery and almost every organ/system. A solid general pathology foundation is essential; keeping updated on new entities is extremely valuable.

Although books and chapters on frozen section diagnosis are available, organized lectures are rarely focused on frozen section diagnostic skills and pitfalls, particularly in the molecular era. Intimate mentoring around the microscope mimicking real time frozen section analysis has not been previously used.

This course addresses diagnosis under pressure and provides practicing pathologists and pathologists-in-training with guidance on how to handle diagnostic dilemmas on the frozen section service, avoid equivocation and effectively communicate with surgeons.



  • Understand the common clinical scenarios and indications that frozen section diagnoses aid in determining the surgical procedure.
  • Become familiar with the common and critical artifacts to avoid misinterpretation.
  • Improve diagnostic skills during the frozen section procedure with enhanced confidence, competence and efficiency, thereby reducing turn-around-time.
  • Understand that deferral is a valid option to avoid uncertain interpretation and potential errors.
  • Enhance communication with the operating surgeon, particularly when the histomorphology is uncertain, and there is potential for harmful error.


  • Qihui (Jim) Zhai, MD

    Mayo College of Medicine; Mayo Clinic Florida


  • Gregory N. Fuller, MD, PhD
    MD Anderson Cancer Center
  • John A. Hart, MD
    University of Chicago
  • Pei Hui, MD, PhD
    Yale University School of Medicine
  • Peter A. Humphrey, MD, PhD
    Yale University School of Medicine
  • Cesar Moran, MD
    The University of Texas MD Anderson Cancer Center

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the United States and Canadian Academy of Pathology and ARP Press. The United States and Canadian Academy of Pathology is accredited by the ACCME to provide continuing medical education for physicians.

The United States and Canadian Academy of Pathology designates this live activity for a maximum of 24 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

USCAP is approved by the American Board of Pathology (ABPath) to offer Self-Assessment credits (SAMs) for the purpose of meeting the ABPath requirements for Continuing Certification (CC).

Physicians can earn a maximum of 24 SAM credit hours.

USCAP records courses at the Interactive Learning Center for future educational purposes. By registering for this course, you consent that your likeness may be used by USCAP.


Cancellations will be assessed an administrative charge of 25% of the total registration fee. There will be no refunds for cancellations within 14 days of the event. The Academy is not responsible for travel expenses incurred as a result of an event cancellation.

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